Guanidinium hydrochloride ≥99%, white crystalline powder optical density grade

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Synonyms: Guanadine hydrochloride, Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidine HCI, Guanidine chloride, Guanidinium chloride, Guanidine hydrochloride

0215121080 0215121090 0215121091
IC15121080EA 81.73 USD
IC15121080 IC15121090 IC15121091
Guanidinium hydrochloride ≥99%, white crystalline powder optical density grade
Guanidinium hydrochloride

Guanidine Hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of proteins.


This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies and be used for the recovery of periplasmic proteins. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. It is also used in the isolation of RNA to dissociate the nucleoprotein into its nucleic acid and protein moieties. It is an inhibitor of RNase.

Formula: NH₂C(=NH)NH₂·HCl
MW: 95.53 g/mol
MDL Number: MFCD00013026
CAS Number: 50-01-1
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Specification Test Results

Identity Test Passes
Purity ~99%
FTIR Conforms to Standard
Melting Point 180 - 190 °C
OD260 (6.0 M aq soln) ≤0.03
Solubility (6.0 M aq soln) C Clear, Colorless Solution

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