L(+)-Histidine ≥99%, crystalline powder

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IC10195480EA 235.16 USD
IC10195480 IC10195490 IC10195491 75875-586 75875-588
L(+)-Histidine ≥99%, crystalline powder
L(+)-Histidine

L-histidine is an essential amino acid with a basic side chain, and is hydrophilic in character


Precursor of histamine by action of histidine decarboxylase.


It contains an imidazole group in the side chain. Histidine is biosynthesized from ATP, 5-phosphoribosyl-1-pyrophosphate (PRPP), and glutamine. In turn, histidine is degraded to glutamate by histidase, urocanase, and imidazolonepropionase via the formation of urocanate, 4-imidazolone 5-propionate, and N-formiminoglutamate.


L-Histidine has been used to study cultures of the human T-lymphoblastic leukemia cell line MOLT-4 to study modulation of apoptosis. Exogenous histidine has been shown to enhance the biosynthesis of lovastatin by cultured Aspergillus terreus. Histidine has been utilized as a single nitrogen source to probe swarming in Pseudomonas aeruginosa on agar. It is generally used in media preparation.


Soluble 50 mg/mL in 0,5 M HCl.

Formula: C₆H₉N₃O₂
MDL Number: MFCD00064315
CAS Number: 71-00-1
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Specification Test Results

Synonyms Glyoxaline-5-Alanine; (S)-2-Amino-3-(4-imidazolyl)propionic acid
Form White Crystalline Powder
Storage Store at Room Temperature.
Optical Rotation 11.0° to 13.5° (c=10, 4N HCl)
pH 7.0 - 8.5 (1% aq soln)
Solubility Soluble 50 mg/mL in 0.5 M HCl.

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