Anti-CD4 Rat Antibody (PE (Phycoerythrin)-Cy7®) [clone: GK1.5]

Supplier: Tonbo Biosciences
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60-0041-U025 60-0041-U100
10141-038EA 66 USD
10141-038 10141-040
Anti-CD4 Rat Antibody (PE (Phycoerythrin)-Cy7®) [clone: GK1.5]
Antibodies
The GK1.5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.

The GK1.5 antibody isMore Product Information
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