Anti-FOXP3 Rat Antibody (APC (Allophycocyanin)) [clone: MF23]

Supplier: Tonbo Biosciences

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C57Bl/6 splenocytes were stained with PE Anti-Mouse CD4 (50-0042), followed by intracellular staining with 0.25 ug APC Anti-Mouse Foxp3 (20-0191) (right panel) or 0.25 ug APC Rat IgG2b isotype control (left panel).

C57Bl/6 splenocytes were stained with PE Anti-Mouse CD4 (50-0042), followed by intracellular staining with 0.25 ug APC Anti-Mouse Foxp3 (20-0191) (right panel) or 0.25 ug APC Rat IgG2b isotype control (left panel).

20-0191-U025 20-0191-U100

10140-998EA 124.3 USD

10140-998 10141-000

Anti-FOXP3 Rat Antibody (APC (Allophycocyanin)) [clone: MF23]

Antibodies

The MF23 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is a member of the forkhead box or winged helix family of transcription factors and is expressed at constitutively high levels in Treg cells. Forced expression of Foxp3 in conventional T cells results in the upregulation of Treg associated molecules such as CD25, CTLA-4, and GITR and is sufficient to impart suppressive functional activity to these cells.

Type: Primary
Antigen: Foxp3
Clonality:
Clone: MF23
Conjugation: APC
Epitope:
Host: Rat
Isotype: IgG2b
Reactivity: Mouse

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