Factor Xa Protease, New England Biolabs
Supplier: W.u.G. Dickgießer GmbHTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
Factor Xa cleaves after the arginine residue in its preferred cleavage site Ile-(Glu or Asp)-Gly-Arg
It will sometimes cleave at other basic residues, depending on the conformation of the protein substrate. The most common secondary site, among those that have been sequenced, is Gly-Arg. There seems to be a correlation between proteins that are unstable in E. coli and those that are cleaved by Factor Xa at secondary sites; this may indicate that these proteins are in a partially unfolded state. Factor Xa will not cleave a site followed by proline or arginine.
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...