Supplier: Adipogen
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AG-40B-0074-C050 AG-40B-0074-3050
102515-538EA 249.23 USD
102515-538 102515-540
Proteins and Peptides
TNF-R1 is a receptor for TNF-alpha and homotrimeric lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
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