Anti-Sirtuin Mouse Monoclonal Antibody [clone: S2R233-1]

Supplier: Adipogen
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AG-20A-0076-C050 AG-20A-0076-C100
102514-186EA 249.23 USD
102514-186 102514-188
Anti-Sirtuin Mouse Monoclonal Antibody [clone: S2R233-1]
Antibodies
Sirtuin-2 is a NAD-dependent protein deacetylase, which deacetylates the 'Lys-40' of a-tubulin. It is involved in the control of mitotic exit in the cell cycle. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer's disease are associated with sirtuins. Selective inhibition of Sirtuin-2 achieves neuroprotection and identifies Sirtuin-2 to be a potential therapeutic avenue in Huntington's and Parkinson's disease.

Type:
Antigen: Sirtuin
Clonality: Monoclonal
Clone: S2R233-1
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG2b kappa
Reactivity: Human
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