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Description: CD62E represents the 97 kDa type I transmembrane glycoprotein E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). It is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial attachment and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues. CD62P is a 140 kDa membrane glycoprotein formerly known as platelet activation-dependent granule membrane protein (PADGEM) or GMP-140. It is expressed on platelets, megakaryocytes, and epithelium. It is thought to mediate the adhesive interactions of neutrophils and monocytes with endothelium in inflammatory responses and of activated platelets to neutrophils and monocytes in hemostasis. The monoclonal antibody 1.2B6 recognizes a common epitope shared by CD62E and CD62P.
Catalog Number: 100246-006
Supplier: Southern Biotechnology


Description: FITC Anti-Human IgE antibody for use in western blotting assays.
Catalog Number: 103265-686
Supplier: Southern Biotechnology


Description: HRP Anti-Hamster IgG3 antibody for use in ELISA assays.
Catalog Number: 103264-676
Supplier: Southern Biotechnology


Description: CD90 (Thy-1) is a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily consisting of a single V-set domain. The Thy-1.2 alloantigen is expressed on all thymocytes, peripheral T lymphocytes, and some intraepithelial T cells of most mouse strains. It is also expressed in the brain and at varying levels on other non-lymphoid tissues. The 30-H12 monoclonal antibody does not cross react with mouse and rat strains bearing the Thy-1.1 alloantigen (e.g., AKR/J, PL).
Catalog Number: 100243-696
Supplier: Southern Biotechnology


Description: The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid production of primitive hematopoietic progenitor cells. A variety of cytokines act synergistically with SCF to stimulate proliferation and differentiation of bone marrow progenitor cells. For example, SCF plus IL-7 can stimulate the combined myeloid and B cell differentiation of uncommitted hematopoietic progenitor cells. SCF/c-Kit also participates in erythropoiesis in both the bone marrow and spleen. Loss-of-function mutations for SCF/c-Kit lead to a variety of pleiotropic developmental defects while gain-of-function mutations can lead to constitutive activation of the kit receptor and links to cancer. Examples of the former are mast cell deficiency and severe macrocytic anemia while the latter mutation has been identified in mastocytomas.
Catalog Number: 100243-996
Supplier: Southern Biotechnology


Description: Chicken Bu-1, a product of the Bu-1a and Bu-1b alleles, is a type I transmembrane glycosylated disulfide-linked homodimer. The monoclonal antibody AV20 recognizes a monomorphic determinant on the Bu-1 B cell-associated alloantigens of both RPL 6(3) (Bu-1a) and 7(2) (Bu-1b) lines of inbred chickens. The antibody also identifies B cells in partially inbred birds. Bu-1 is found on 85-90% of bursal cells, 2-8% of thymocytes, 15-27% of spleen cells, and 2-18% of peripheral blood cells. It is also expressed on subsets of macrophages and monocytes but not on granulocytes, erythrocytes, or thrombocytes. The monoclonal antibody AV20 does not cross react with turkey cells when analyzed by flow cytometry.
Catalog Number: 100245-600
Supplier: Southern Biotechnology


Description: CD3 is a member of the T cell receptor-associated CD3 complex. The monoclonal antibody CT-3 recognizes a complex of at least three polypeptides of Mr 20, 19, and 17 kDa (two of which are N-glycosylated) on chicken T cells. The antibody also coprecipitates a polypeptide of 90 kDa from digitonin solubilized T cell lysates, which can be reduced to two polypeptides of Mr 50 and 40 kDa.
Catalog Number: 103265-150
Supplier: Southern Biotechnology


Description: FITC Anti-Human IFN-gamma antibody for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.
Catalog Number: 101442-594
Supplier: Southern Biotechnology


Description: CD90 (Thy-1), a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes, and neurons of all mouse strains. The monoclonal antibody G7 stimulates T-cell proliferation and IL-2 secretion via signaling through the T-cell receptor/CD3 complex. G7 has also been reported to promote apoptosis of thymocytes and CTL clones and to mediate adhesion of thymocytes to thymic stroma.
Catalog Number: 100243-674
Supplier: Southern Biotechnology


Description: Goat Anti-Human Kappa-FITC antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Catalog Number: 100244-336
Supplier: Southern Biotechnology


Description: Mouse IgM-Biotin for use as a control in flow cytometry and immunohistochemistry assays.
Catalog Number: 100241-880
Supplier: Southern Biotechnology


Description: Purified Anti-Human IgG1 Hinge antibody for use in ELISA, flow cytometry, immunohistochemistry, western blotting, separation, purification, and multiplex assays.
Catalog Number: 100245-710
Supplier: Southern Biotechnology


Description: AP Anti-Rat IgG1 antibody for use in ELISA, immunohistochemistry, and ELISpot assays.
Catalog Number: 101442-822
Supplier: Southern Biotechnology


Description: Goat Anti-Rhesus IgG(H+L)-AP antibody for use in ELISA, immunocytochemistry, and western blotting assays.
Catalog Number: 100245-208
Supplier: Southern Biotechnology


Description: The CD23 antigen is the low affinity IgE Fc receptor, which is a 45-49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells) and can also be found on the surface of T cells, macrophages and platelets. It is distinct from the high affinity IgE receptors found on basophils and mast cells which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a “membrane bound cytokine," in that the soluble cleavage products of CD23 are themselves able to act as cytokines in vitro.
Catalog Number: 100243-312
Supplier: Southern Biotechnology


Description: Goat Anti-Human Kappa-AP antibody for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.
Catalog Number: 100244-340
Supplier: Southern Biotechnology


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