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Description: This antibody recognizes cytokeratin polypeptides ranging from 40 to 58 kDa, corresponding to cytokeratins 5, 6, 8,17 and 19. It shows a broad pattern of reactivity with human epithelial tissues from simple glandular epithelia to stratified squamous epithelia, like epidermis, mammary gland ducts and tracheal epithelium.
Catalog Number: 76633-162
Supplier: Diagnostic Biosystems


Description: This antibody reacts with a 220 kDa protein. CD15 plays a role in mediating phagocytosis, bactericidal activity and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. CD15 is also expressed in Reed-Sternberg cells and some epithelial cells. CD15 is very useful in the identification of Hodgkin disease.
Catalog Number: 76634-378
Supplier: Diagnostic Biosystems


Description: Mesothelin is a glycocylphosphotidylianositol-linked cell-surface glycoprotein, which is present on the surface of normal mesothelium and is overexpressed in many patients with epithelial ovarian cancer and malignant mesotheliomas.
Catalog Number: 76634-884
Supplier: Diagnostic Biosystems


Description: Inhibin is a dimeric glycoprotein hormone from the TGF-β family made of β and α subunits. This antibody recognizes the 32kDa α subunit of human inhibin. Inhibin α is expressed in a wide variety of human tissues, such as brain, prostate, adrenal, granulose cells of ovary, sertoli cells of testis and in fetoplacental unit.
Catalog Number: 76633-904
Supplier: Diagnostic Biosystems


Description: This antibody reacts with B cell follicles in human lymphoid tissues. The mantle zones give a mosaic pattern, while the germinal centers show a coarse meshwork pattern of staining. This antibody stains free as well as bound kappa light chains. This antibody does not react with human lambda light chain.
Catalog Number: 99990-900
Supplier: Diagnostic Biosystems


Description: This antibody recognizes an uncharacterized antigen present in both adults and fetal normal hepatocytes to produce a distinct granular cytoplasmic staining. This antibody stains majority of hepatocellular carcinomas.
Catalog Number: 95024-584
Supplier: Diagnostic Biosystems


Description: This antibody is specific to CD74. This antibody can be used for the identification of B cell lymphomas and leukemias. It also stains activated neoplastic cells in T cell lymphomas and Sternberg-Reed cells.
Catalog Number: 76633-382
Supplier: Diagnostic Biosystems


Description: Buffer for washing tissue during IHC.
Catalog Number: 99990-062
Supplier: Diagnostic Biosystems


Description: This antibody reacts with a glycoprotein of 110 kDa, expressed as intracytoplasmic molecule. It stains macrophages in a wide variety of tissues. Myeloid precursor cells and peripheral granulocytes are negative. The PG-M1 differs from EMB11 (CD68) because of its non-reactivity with granulocytes and their precursor cells.
Catalog Number: 76633-286
Supplier: Diagnostic Biosystems


Description: This antibody reacts with a neuraminidase sensitive oligosaccharide side chain of a glycoconjugate present in immature melanosomes. It reacts with junctional and blue nevus cells. Non-melanocytic cells are negative.
Catalog Number: 76633-852
Supplier: Diagnostic Biosystems


Description: This antibody reacts with a protein of 81 kDa. Ezrin serves as a tyrosine kinase substrate and is phosphorylated in EGF-stimulated cells. Ezrin is a cytoplasmic protein, enriched in microvilli and other cell surfaces. Ezrin has an actin-binding capacity. Ezrin is expressed in epithelial cells but not in mesenchymal cells. Ezrin is also expressed by certain epithelial tumors, such as renal cell adenocarcinomas.
Catalog Number: 95024-548
Supplier: Diagnostic Biosystems


Description: This antibody reacts with the mu-chains of human IgM. Nonspecific antibodies have been removed by solid-phase adsorption.
Catalog Number: 99991-078
Supplier: Diagnostic Biosystems


Description: This antibody is specific to 53 kDa protein, expressed on activated platelets. CD63 is a lysosomal membrane glycoprotein that is translocated to plasma membrane after platelet activation. It is also expressed on granulocytes, B cells and T cells.
Catalog Number: 76633-628
Supplier: Diagnostic Biosystems


Description: The Picro-Sirius Red Stain Kit (For Collagen) is intended for use in the histological visualization of collagen I and III fibers in addition to muscle in tissue sections.
Catalog Number: 10065-176
Supplier: Diagnostic Biosystems


Description: This antibody reacts with human factor VIII related antigen. It stains endothelial cells and megakaryocytes in various human tissues. This antibody does not cross-react with any other cell types.
Catalog Number: 99991-068
Supplier: Diagnostic Biosystems


Description: The common acute lymphoblastic leukemia antigen (CALLA/CD10) is a single-pass type II transmembrane metallo-endopeptidase that cleaves and inactivates a variety of peptide growth factors important for signal transduction including the enkephalins, bombesin and substance P. CD10 is expressed by a number of hematopoietic cells such as immature T and B cells, B cells of the germinal centers of lymphoid follicles and granulocytes. It also reacts with a variety of non-hematopoietic cells, including epithelial cells in GI tract and kidney tubular. In liver, the bile canaliculi shows a moderate to strong staining. CD10 has been used for the identification and classification of certain types of malignant lymphoma and leukemia. CD10 is expressed in a high percentage of cases of acute lymphoblastic leukemia, follicular lymphoma, Burkitt's lymphoma, some hematopoietic tumors, and chronic myelogenous leukemias in lymphoid blast crisis. It is also known to be a marker of endometrial stromal cells. It is helpful in differentiating endometrial stromal sarcoma (ESS) from uterine cellular leiomyoma (UCL) and uterine leiomyosarcoma (ULS).
Catalog Number: 76634-356
Supplier: Diagnostic Biosystems


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