Description: Elite PAP pen is a special marking pen that provides a thin film-like green-tinged hydrophobic barrier when a circle is drawn around a specimen on a slide. This water repellent barrier keeps staining reagents localized on the tissue sections, prevents mixing of reagents when differentially staining two sections on the same slide, and allows use of less reagents per section. Insoluble in alcohol and acetone, PAP Pen markings can be optionally removed with xylene after the staining procedure is complete.

Catalog Number: 99990-104

Supplier: Diagnostic Biosystems

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Description: Elite mini PAP pen is a special marking pen that provides a thin film-like green-tinged hydrophobic barrier when a circle is drawn around a specimen on a slide. This water repellent barrier keeps staining reagents localized on the tissue sections, prevents mixing of reagents when differentially staining two sections on the same slide, and allows use of less reagents per section.

Catalog Number: 95025-252

Supplier: Diagnostic Biosystems

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Description: This kit stains Helicobacter pylori bacteria in paraffin tissue sections

Catalog Number: 95027-196

Supplier: Diagnostic Biosystems

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Description: This antibody is specific to macrophages in a wide variety of human tissues. It reacts with myeloid precursors and peripheral blood granulocytes. It also stains a cell population known as plasmacytoid T cells.

Catalog Number: 99990-918

Supplier: Diagnostic Biosystems

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Description: This antibody reacts with two glycoproteins of 34 and 49 kDa present on the epithelial cells. It stains with simple epithelia and basal layers of stratified non-keratinized squamous epithelium.

Catalog Number: 99990-234

Supplier: Diagnostic Biosystems

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Description: This antibody reacts with CD21 antigen of MW 145 kDa, present on the surface of mature B cells. The antigen is present at high density on follicular dendritic cells. CD21 is involved in transmitting growth-promoting signals to the interior of the B cell.

Catalog Number: 76633-114

Supplier: Diagnostic Biosystems

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Description: Cyclin D1 belongs to the Cyclin D family. Cyclin D1 is required for the cell cycle G1/S transition. Amplification or overexpression of Cyclin D1 plays a pivotal role in the development of various human cancers including breast cancer, colon cancer, melanoma, prostate cancer and lymphoma. It is useful to differentiate mantle cell lymphoma from small cleaved cell lymphoma. Rabbit monoclonal antibodies to Cyclin D1 showed the highest sensitivity to detect this antigen in formalin fixed paraffin embedded tissue as compared to several other clones.

Catalog Number: 76634-816

Supplier: Diagnostic Biosystems

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Description: This buffer is a concentrated antigen unmasking solution and is free from heavy metals

Catalog Number: 99990-100

Supplier: Diagnostic Biosystems

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Description: The is a heavy metal free antigen unmasking solution provided in a convenient 10X concentrate

Catalog Number: 10064-756

Supplier: Diagnostic Biosystems

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Description: This antibody reacts with human isoenzymes of neuron specific enolase containing γ subunits. This antibody gives a specific staining in neurons of the brain, in islets of Langerhans in pancreas and in peripheral nerves of the skin. No staining with other tissue types has been seen.

Catalog Number: 95025-098

Supplier: Diagnostic Biosystems

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Description: This antibody recognizes cytokeratin polypeptides ranging from 40 through 58kDa, corresponding to cytokeratins 5, 6, 8,17 and 19. It shows a broad pattern of reactivity with human epithelial tissues from simple glandular epithelia to stratified squamous epithelia, like epidermis, mammary gland ducts and tracheal epithelium.

Catalog Number: 99990-216

Supplier: Diagnostic Biosystems

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Description: This antibody recognizes keratin polypeptides of 68, 58, 56.5 and 50 kDa in the stratum corneum. The antibody reacts with squamous, ductal and other complex epithelia. It stains adenocarcinomas, breast, pancreas, bile duct, salivary gland and transitional cell carcinomas.

Catalog Number: 76633-186

Supplier: Diagnostic Biosystems

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Description: This antibody is specific to a 33 kDa polypeptide present on the majority of B cells in peripheral blood and lymphoid tissue. No reactivity with other hematopoietic cells has been observed.

Catalog Number: 76633-096

Supplier: Diagnostic Biosystems

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Description: The HMB45 clone reacts with a neuraminidase-sensitive oligosaccharide side chain of a glycoconjugate present in immature melanosomes. The HMB45-reactive antigen is present in cutaneous melanocytes, prenatal and infantile retinal pigment epithelium and melanoma cells and is thought to be oncofetal in nature. This antibody has been shown to label the majority of melanomas. Clone A103 recognizes a protein of 20 kDa, identified as MART-1 (melanoma antigen recognized by T cells-1) or Melan-A. Melan-A is a useful addition to melanoma panels as it is apparently specific for melanocytic lesions. Studies have also shown that MART-1 is more sensitive than HMB45 when labeling metastatic melanomas. Tyrosinase is a key enzyme involved in the initial stages of melanin biosynthesis. Studies have shown tyrosinase to be a more sensitive marker when compared to HMB45 and MART-1. It has been shown to label a higher percentage of desmoplastic melanomas than HMB45. The combination of HMB45, MART-1 and tyrosinase make this triple antibody cocktail a first-order pan melanoma screener.

Catalog Number: 76634-402

Supplier: Diagnostic Biosystems

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Description: This antibody is specific to two proteins of 185 kDa and 145 kDa, identified as two isoforms of neural cell adhesion molecules (NCAM/CD56). NCAM is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytoma and neuroblastoma.

Catalog Number: 99990-496

Supplier: Diagnostic Biosystems

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Description: This antibody is specific to an epitope on the N-terminus of ACTH. This antibody stains corticotrophs in the adenohypophysis and is useful in the classification of pituitary adenomas.

Catalog Number: 76633-512

Supplier: Diagnostic Biosystems

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