Description: This antibody recognizes human retinoblastoma gene protein. Rb gene, a prototype of tumor suppressor genes, has been associated with development and/or progression of bladder cancer as well as sarcoma and small cell lung cancer. Functional Rb gene loss has been reported to occur in bladder cancer and osteosarcoma. A significantly poorer tumor-free survival rate was noted for those patients who had a tumor with an altered Rb protein with or without vascular invasion.

Catalog Number: 76634-360

Supplier: Diagnostic Biosystems

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Description: Multiple myeloma oncogene-1 (MUM1) is a 50kDa protein encoded by the MUM1 gene. This antibody stains MUM1 protein, which is expressed in a subset of B cells in the light zone of the germinal center, plasma cells, activated T cells and a wide spectrum of related hematolymphoid neoplasms. This antibody is useful in the sub classification of lymphoid malignancies.

Catalog Number: 76633-848

Supplier: Diagnostic Biosystems

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Description: This antibody reacts with the zymogen as well as the activated form of cathepsin D. It stains fibroblasts and macrophages strongly but stains weakly with the myoepithelial cells of breast. It stains the sweat ducts and glands in the skin, islets cells and granules of pancreatic acini.

Catalog Number: 95024-934

Supplier: Diagnostic Biosystems

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Description: Anti-Cytokeratin (CAM 5.2) reagent has a primary reactivity with human keratin proteins that correspond to Moll’s peptides #7 and #8, Mr 48 and 52 kilodaltons (kd), respectively. Cytokeratin 7 and 8 are present on secretory epithelia of normal human tissue but not onstratified squamous epithelium. Anti-Cytokeratin (CAM 5.2) stains most epithelial-derived tissue, including liver, renal tubular epithelium, and hepatocellular and renal cell carcinomas. Anti-Cytokeratin (CAM 5.2) might not react with some squamous cell carcinomas.

Catalog Number: 76633-984

Supplier: Diagnostic Biosystems

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Description: This antibody reacts with free as well as bound kappa light chains. Contaminating antibodies have been removed by solid phase adsorption.

Catalog Number: 76634-310

Supplier: Diagnostic Biosystems

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Description: This antibody is specific for α-skeletal muscle actinin and α-cardiac actinin. It stains Z lines and dots in stress fibers of myotubes in skeletal and cardiac muscle but not in non-sarcomeric muscle elements.

Catalog Number: 99990-450

Supplier: Diagnostic Biosystems

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Description: This antibody reacts with the heavy chain present in all types of human IgM. It stains B cell follicles in human lymphoid tissues. In lymphoid tissues, IgM containing plasma cells stain strongly but immune complexes are usually undetectable.

Catalog Number: 76634-624

Supplier: Diagnostic Biosystems

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Description: This antibody reacts with the 54 kDa (flagellin) of <i>H. pylori</i>. The antibody stains the bacteria present on the surface of the epithelium or in the cytoplasm of the epithelial cells.<i> H. pylori</i> is known to cause peptic ulcer and chronic gastritis in humans.

Catalog Number: 76634-532

Supplier: Diagnostic Biosystems

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Description: This antibody recognizes keratin polypeptide of 54 kDa. It stains a number of epithelial cells including ductal and glandular epithelia. Stratified squamous epithelia are positive but transitional epithelium of the urinary tract does not show any staining. This antibody labels adenocarcinomas and transitional carcinomas but does not react with squamous cell carcinomas.

Catalog Number: 76634-346

Supplier: Diagnostic Biosystems

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Description: Clone number 2B11+PD7/26, The human leukocyte common antigen is a family of five or more high molecular weight glycoproteins of MW 180, 190, 205 and 220 kD, present on the surface of the majority of human leucocytes. This antibody labels lymphoid cells. .

Catalog Number: 99990-832

Supplier: Diagnostic Biosystems

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Description: P16 is a mitotic inhibitor protein. It competes with D-type cyclins to bind to cdk4 and cdk6. It acts as tumor suppressor and inhibits the progression of cells through the G1 phase of the cell cycle.

Catalog Number: 76634-560

Supplier: Diagnostic Biosystems

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Description: Wilms tumor-1 (WT-1), is a gene involved in the induction of Wilms tumor, a pediatric renal malignancy. Wilms tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilms tumor and mesothelioma.

Catalog Number: 76634-452

Supplier: Diagnostic Biosystems

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Description: The Mouse UnoVue HRP/DAB Detection System is a polymer-based 1-step horseradish peroxidase-labeled detection system for immunohistochemistry. This kit can detect mouse IgG and IgM antibodies, with significantly lower background than biotin/avidin detection systems.

Catalog Number: 10065-156

Supplier: Diagnostic Biosystems

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Description: This antibody reacts with the human C1q complement. Traces of contaminating antibodies have been removed by solid phase absorption with human plasma proteins. This antibody is well suited for tissue section staining but may also be used for other applications.

Catalog Number: 99990-048

Supplier: Diagnostic Biosystems

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Description: This kit stains Gram-positive and Gram-negative bacteria in paraffin tissue sections

Catalog Number: 95027-194

Supplier: Diagnostic Biosystems

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Description: This kit stains acid mucins, carboxylated and sulfated mucosubstances (except strongly sulfated mucosubstances) in paraffin tissue sections

Catalog Number: 95027-174

Supplier: Diagnostic Biosystems

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