You Searched For: Span® 60


7  results were found

Sort Results

List View Easy View (new)
SearchResultCount:"7"
Description: Mucin 5AC (MUC5AC), Monoclonal antibody, Clone: MUC5AC/917 + 45M1, Host: Mouse, Species reactivity: Hedgehog, Monkey, Pig, Cat, Rat, Human, Chicken, Isotype: IgG1, kappa, Conjugate: purified, Synonyms: Apomucin Major Airway Glycoprotein, Size: 500uL
Catalog Number: 75962-044
Supplier: Biotium


Description: WT1 (Wilm's Tumor 1), Monoclonal antibody, Clone: WT1/857, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Recombinant protein corresponding to residues 1-181 of human WT1, Synonyms: WT1; AWT1, Size: 100uL
Catalog Number: 75979-974
Supplier: Biotium


Description: This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Catalog Number: 75977-926
Supplier: Biotium


Description: CD13 Monoclonal antibody, Clone: WM15, Host: Mouse, Conjugate: CF647, Species reactivity: Human, Immunogen: Recombinant human VCAM1 protein, Isotype: IgG1, kappa, Synonyms: CD106; INCAM-100; L1CAM; Vascular Cell, Application: IF, IHC, Size: 100uL
Catalog Number: 75887-300
Supplier: Biotium


Description: CD50 Monoclonal antibody, Clone: 186-2G9, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, Conjugate: purified, Immunogen: Stimulated human leukocytes, Synonyms: ICAMR, Intercellular adhesion molecule 3 (ICAM3), Application: IF, IHC, Size: 100uL
Catalog Number: 75915-032
Supplier: Biotium


Description: PTH / Parathyroid Hormone (N-Terminal), Monoclonal antibody, Clone: PTH/1174, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: CF488A, Immunogen: synthetic peptide from N-terminal of PTH polypeptide, Synonyms: Parathyrin, Size: 100uL
Catalog Number: 75973-414
Supplier: Biotium


Description: At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Catalog Number: 75889-670
Supplier: Biotium


Description: This antibody recognizes a myeloid associated differentiation antigen in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell type in human tissues. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of human and monkey myeloid cells. This MAb is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.
Catalog Number: 75968-340
Supplier: Biotium


Description: This antibody recognizes a cell surface glycoprotein of 80-95 kDa (CD44) on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95 kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®555 is a bright orange-red fluorescent dye (Ex/Em 555/565 nm) that is compatible with super-resolution imaging by STORM.
Catalog Number: 75912-698
Supplier: Biotium


Description: Myosin, Smooth Muscle Heavy Chain, Monoclonal antibody, Clone: MYH11/923 + SMMS-1, Host: Mouse, Species reactivity: Human, Rat, Isotype: IgG's, Conjugate: CF405S, Immunogen: Recombinant human MYH11 protein, Synonyms: AAT4, Application: IF, Size: 500uL
Catalog Number: 75965-088
Supplier: Biotium


Description: Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
Catalog Number: 75916-288
Supplier: Biotium


Description: Von Willebrand Factor, Monoclonal antibody, Clone: 3E2D10 + VWF635, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Recombinant human vWF fragment spanning aa 845-949, Synonyms: Coagulation Factor VIII, Size: 100uL
Catalog Number: 75979-130
Supplier: Biotium


Description: This antibody recognizes a phosphor-protein of 45 kDa, identified as MyoD1. This MAb does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
Catalog Number: 75964-816
Supplier: Biotium


Description: LysoView™ dyes label lysosomes in live cells, and are available with blue, green, visible red, and far-red fluorescence.
Catalog Number: 76221-662
Supplier: Biotium


Description: Biocytin (ε-Biotinoyl-L-lysine) is a cellular tracer that can be introduced into cells by microinjection.
Catalog Number: 89139-610
Supplier: Biotium


Description: Cytokeratin 17 (CK17) is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as an epithelial stem cell marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. The histologic differentiation of ampullary cancer, intestinal vs. pancreatobiliary, is very important for treatment. Usually anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
Catalog Number: 75916-352
Supplier: Biotium


2,417 - 7 of 7