Description: Plerixafor (AMD3100) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively.

Catalog Number: 103548-034

Supplier: Selleck Chemicals

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Description: Thiazovivin is a novel ROCK inhibitor with IC50 of 0.5 μm in a cell-free assay, promotes hESC survival after single-cell dissociation.

Catalog Number: 101763-282

Supplier: Selleck Chemicals

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Description: Alisertib (MLN8237) is a selective aurora A inhibitor with IC50 of 1.2 nM in a cell-free assay

Catalog Number: 101760-666

Supplier: Selleck Chemicals

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Description: Tacrolimus is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin creating a new complex.

Catalog Number: 101758-896

Supplier: Selleck Chemicals

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Description: Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with K_i of 140 nM in a cell-free assay, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.

Catalog Number: 101763-968

Supplier: Selleck Chemicals

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Description: Clofarabine inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.

Catalog Number: 101757-922

Supplier: Selleck Chemicals

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Description: Captisol (SBE-β-CD) is a chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of drugs.

Catalog Number: 103544-514

Supplier: Selleck Chemicals

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Description: Tadalafil is a PDE-5 inhibitor with IC₅₀ of 1.8 nM.

Catalog Number: 101763-000

Supplier: Selleck Chemicals

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Description: Pimaricin ( synonym Natamycin), a natural and versatile anti-fungal agent during fermentation by the bacterium <i>Streptomyces natalensis</i>, commonly found in soil, with little to no flavour interference.

Catalog Number: 101760-840

Supplier: Selleck Chemicals

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Description: CB1954(Tretazicar) is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. It can be activated by NAD(P)H quinone oxidoreductase 2.

Catalog Number: 103547-212

Supplier: Selleck Chemicals

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Description: Trametinib is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2.

Catalog Number: 101759-298

Supplier: Selleck Chemicals

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Description: Busulfan, Purity: 99.90 %, Cas number: 55-98-1, Molecular Weight: 246.3, Form: powder, cell cycle non-specific alkylating antineoplastic agent, DMSO Solubility: 49 mg/mL (198.94 mM), Storage: -20 deg C, Size: 50MG

Catalog Number: 103539-572

Supplier: Selleck Chemicals

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Description: GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM

Catalog Number: 101759-288

Supplier: Selleck Chemicals

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Description: Escitalopram oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.

Catalog Number: 103543-382

Supplier: Selleck Chemicals

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Description: Tofacitinib citrate (CP-690550 citrate) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively.

Catalog Number: 101763-348

Supplier: Selleck Chemicals

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Description: Imiquimod is a novel synthetic agent with immune response modifying activity.

Catalog Number: 101759-614

Supplier: Selleck Chemicals

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