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Description: Mdivi-1 is a selective inhibitor of mitochondrial division in yeast and mammalian cells which acts via inhibiting the mitochondrial division dynamin. In cells, Mdivi-1 inhibits apoptosis by inhibiting mitochondrial outer membrane permeabilization. Mdivi-1 causes the rapid (50= ~10µM. In yeast, time-lapse fluorescence microscopy revealed no detectable mitochondrial division after treatment with Mdivi-1. It inhibits Dnm1 GTPase activity in a dose dependent manner with an estimated IC50 of 1-10µM but is not a general inhibitor of GTPases.
Catalog Number: 89156-982
Supplier: Enzo Life Sciences


Description: 3-(2,4-Dichloro-5-methoxyphenyl)-2-mercaptoquinazolin-4(3H)-one, Purity: 98%, CAS Number: 338967-87-6, Appearance: Form: Crystal - Powder / Colour: White - Slightly pale yellow, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 1mg
Catalog Number: 77685-717
Supplier: AMBEED, INC

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