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Description: TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces anchorage-independent transformation in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant Human TGF-α is a 50 amino acid polypeptide (5.5 kDa), which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
Catalog Number: 10781-700
Supplier: PeproTech, Inc.


Description: FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Murine FGF-basic is a 16.3 kDa protein consisting of 145 amino acid residues.
Catalog Number: 10781-868
Supplier: PeproTech, Inc.


Description: VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant Murine VEGF
Catalog Number: 10781-856
Supplier: PeproTech, Inc.


Description: GDNF is a disulfide-linked, homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFRα (α1-α4) receptors. GDNF specifically promotes dopamine uptake and survival, and morphological differentiation of midbrain neurons. Using a Parkinson’s disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional human GDNF ligand is a disulfide-linked homodimer consisting of two 15 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, including Cys-101, which is used for inter-chain disulfide bridging, and others that are involved in the intramolecular ring formation known as the cysteine knot configuration. The calculated molecular weight of Recombinant Human GDNF is 30.4 kDa.
Catalog Number: 10781-228
Supplier: PeproTech, Inc.


Description: Produced from sera of rabbits immunized with highly pure Recombinant Murine MCP-5 (CCL12). Anti­Murine MCP-5 (CCL12)­specific antibody was purified by affinity chromatography and then biotinylated.
Catalog Number: 10775-520
Supplier: PeproTech, Inc.


Description: IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is a species-specific, variably glycosylated cytokine. Recombinant Murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.
Catalog Number: 10780-138
Supplier: PeproTech, Inc.

Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. GRO/MGSA also stimulates mitogenesis in certain human melanoma cells. Recombinant Human GRO-α/MGSA (CXCL1) is a 7.8 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.
Catalog Number: 10773-552
Supplier: PeproTech, Inc.


Description: Produced from sera of goats immunized with highly pure Recombinant Human TNF-α. Anti­Human TNF-α­specific antibody was purified by affinity chromatography employing an immobilized Human TNF-α matrix.
Catalog Number: 10775-182
Supplier: PeproTech, Inc.


Description: Produced from sera of rabbits immunized with highly pure Recombinant Human IFN-γ. Anti­Human IFN-γ­specific antibody was purified by affinity chromatography and then biotinylated.
Catalog Number: 10775-212
Supplier: PeproTech, Inc.


Description: Produced from sera of rabbits immunized with highly pure Recombinant Murine IL-1α. Anti­Murine IL-1α­specific antibody was purified by affinity chromatography employing an immobilized Murine IL-1α matrix.
Catalog Number: 10775-434
Supplier: PeproTech, Inc.


Description: Murine IL-4, Polyclonal Antibody, source: Rabbit, purified by affinity chromatography, cross reactivity: Mouse, Immunogen: E.coli derived Recombinant Murine IL-4, Application: Elisa, Western Blot, pack size: 50ug
Catalog Number: 10775-458
Supplier: PeproTech, Inc.


Description: Produced from sera of rabbits immunized with highly pure Recombinant Human PDGF-BB. Anti­Human PDGF-BB­specific antibody was purified by affinity chromatography and then biotinylated.
Catalog Number: 10775-370
Supplier: PeproTech, Inc.


Description: Produced from sera of rabbits immunized with highly pure Recombinant Human Eotaxin (CCL11). Anti­Human Eotaxin (CCL11)­specific antibody was purified by affinity chromatography employing an immobilized Human Eotaxin matrix.
Catalog Number: 10775-282
Supplier: PeproTech, Inc.


Description: Produced from sera of goats immunized with highly pure Recombinant Human Eotaxin-2 (CCL24). Anti­Human Eotaxin-2 (CCL24)­specific antibody was purified by affinity chromatography and then biotinylated.
Catalog Number: 10775-980
Supplier: PeproTech, Inc.


Description: Produced from sera of rabbits immunized with highly pure Recombinant Rat MCP-1 (CCL2). Anti­Rat MCP-1 (CCL2)­specific antibody was purified by affinity chromatography and then biotinylated.
Catalog Number: 10775-696
Supplier: PeproTech, Inc.


Description: Produced from sera of rabbits immunized with highly pure Recombinant Murine IP-10 (CXCL10). Anti­Murine IP-10 (CXCL10)­specific antibody was purified by affinity chromatography employing an immobilized Murine IP-10 matrix.
Catalog Number: 10776-250
Supplier: PeproTech, Inc.