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Catalog Number: (77134-250)
Supplier: Prosci
Description: Human Recombinant TREM2 Protein (from HEK293 cells)


Catalog Number: (76759-814)
Supplier: Prosci
Description: Anti-ZNF177 Rabbit Polyclonal Antibody


Catalog Number: (10114-322)
Supplier: Prosci
Description: Polyclonal, Host: Goat; Immunogen: PEPT2 antibody was raised against a 13 amino acid synthetic peptide near the C-Terminus of PEPT2; Applications: ELISA


Catalog Number: (77122-196)
Supplier: Prosci
Description: IRF2BP1 Peptide


Catalog Number: (10113-546)
Supplier: Prosci
Description: Polyclonal, Host: Goat, Species Reactivity: Human, Immunogen: LARGE antibody was raised against a 13 amino acid synthetic peptide near the internal region of LARGE (aa 421-433), Tested Applications: ELISA, WB


Catalog Number: (10075-396)
Supplier: Prosci
Description: Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005; Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRalpha1, TRalpha2, TRbeta1 and TRbeta2. TRalpha1, TRbeta1 and TRbeta2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005).


Catalog Number: (10797-074)
Supplier: Prosci
Description: Human bone morphogenetic protein 2 (BMP2) is also known as human BMP-2, BMP-2, BMP2, BMP 2, h-BMP-2, rh-BMP-2, recombinant human BMP-2, recombinant BMP-2, BMP, is a member of the BMP subgroup belonging to the TGF-b superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. As implied by its name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP2 has been demonstrated to potently induce osteoblast differentiation in a variety of cell types, and induce apoptosis in human myeloma cell lines as a novel function.


Catalog Number: (76012-536)
Supplier: Prosci
Description: HEMGN regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).


Catalog Number: (76012-576)
Supplier: Prosci
Description: The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq].


Catalog Number: (77126-602)
Supplier: Prosci
Description: FZD4 Peptide


Catalog Number: (76753-646)
Supplier: Prosci
Description: Anti-KCNJ11 Rabbit Polyclonal Antibody


Catalog Number: (76194-888)
Supplier: Prosci
Description: CD8 is a cell surface receptor expressed either as a heterodimer with the beta chain or as a homodimer. A majority of thymocytes and a subpopulation of mature Tcells and NK cells express CD8a. It binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in Tcell development and activation of mature Tcells. For mature Tcells, CD8 and 4 are mutually exclusive, so antibody to CD8 is generally used in conjunction with antibody to CD4. CD8a antibody is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral Tcell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+/CD8-, and in T-lymphoblastic lymphoma/leukemia, they are often co-expressed. It is also found in littoral cell angioma of the spleen.


Catalog Number: (77132-784)
Supplier: Prosci
Description: Human Recombinant IL-37 Protein (from <i>E. coli</i>)


Catalog Number: (10098-534)
Supplier: Prosci
Description: IL-15 (14-15 kD) is a member of the four alpha-helical bundle family of cytokines. It is very similar to IL-2, except that IL-15 has an IL-15 alpha receptor subunit. IL-15 plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes as well as activation of a number of important intracellular signaling molecules. This implies that IL-15 could be essential for the immune responses, allograft rejection, and the pathogenesis of autoimmune diseases.


Catalog Number: (10070-344)
Supplier: Prosci
Description: The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1, 4, 5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.


Catalog Number: (77130-040)
Supplier: Prosci
Description: NANOS1 Peptide


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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