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Image Unavailable-TCA2870-50MG

Afatinib ≥97.0% (by HPLC, total nitrogen)

Catalog Number: (TCA2870-50MG)
Supplier: TCI America
Description: Afatinib ≥97.0% (by HPLC, total nitrogen)

New Product


Image Unavailable-TS46564-2500

Afatinib 96%

Catalog Number: (TS46564-2500)
Supplier: THERMO FISHER SCIENTIFIC CHEMICALS
Description: Afatinib 96%
Image Unavailable-76973-026

Afatinib 99%

Supplier: AMBEED, INC
Description: Afatinib 99%

New Product

Image Unavailable-102992-046

Afatinib ≥95%

Supplier: Adipogen
Description: Afatinib is an irreversible kinase inhibitor and binds to the kinase domains of EGFR (ErbB1), HER2 (ErbB2), and HER4 (ErbB4) to inhibit tyrosine kinase autophosphorylation. This results in a downregulation of ErbB signaling and subsequent inhibition of proliferation of cell lines expressing wild-type EGFR, selected EGFR exon 19 deletion mutations, or exon 21 L858R mutations. It also inhibited in vitro proliferation of cell lines overexpressing HER2. Overall, tumor growth was inhibited by Afatinib very effectively with low nanomolar IC(50) values ranging from approximately 6nM to below 500nM.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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