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Catalog Number: (103265-062)
Supplier: Southern Biotechnology
Description: Donkey Anti-Mouse IgG(H+L)-Biotin antibody with minimal reactivity to human, goat, sheep, bovine, rabbit, chicken, horse, and guinea pig serum proteins for use in ELISA and immunocytochemistry assays.


Catalog Number: (103264-774)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Human IgG-Alexa Fluor 555 antibody for use in immunohistochemistry and western blotting assays.


Catalog Number: (100246-378)
Supplier: Southern Biotechnology
Description: CD79 is a disulfide-linked heterodimer composed of an α chain (CD79a) and a β chain (CD79b) that associates non-covalently with membrane immunoglobulin to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes first appearing on the surface at the pro-B cell stage and remaining through all stages of B cell differentiation prior to plasma cells. Crosslinking of the BCR leads to B cell activation. The monoclonal antibody CB3-1 reacts with the β chain of CD79.


Catalog Number: (100244-288)
Supplier: Southern Biotechnology
Description: Purified Goat F(ab')2 Anti-Human IgG antibody for use in ELISA, flow cytometry, immunohistochemistry, western blotting, ELISpot, separation, and stimulation assays.


Catalog Number: (100244-906)
Supplier: Southern Biotechnology
Description: The SBA Clonotyping System-HRP kit is designed for the isotyping of mouse monoclonal antibodies. It contains 2.5 mg of capture antibody and 1.0 mL of HRP conjugated anti-mouse Ig, mouse IgA, mouse IgG1, mouse IgG2a, mouse IgG2b, mouse IgG3, mouse IgM, mouse , mouse , and ABTS substrate. The kit may also be utilized for quantitative studies of mouse immunoglobulins in samples such as serum, supernatant, and ascites when used in conjunction with the Mouse Immunoglobulin Panel (SB Cat. No. 5300-01).


Catalog Number: (100242-674)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG2a-FITC antibody with minimal reactivity to human proteins for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100243-258)
Supplier: Southern Biotechnology
Description: CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow. The monoclonal antibody 6D5 recognizes the same epitope as the published clone, 1D3.


Catalog Number: (103264-808)
Supplier: Southern Biotechnology
Description: Goat Fab Anti-Rat Ig-HRP antibody with minimal reactivity to mouse proteins for use in ELISA assays.


Catalog Number: (103265-310)
Supplier: Southern Biotechnology
Description: CD11c is a 150 kDa adhesion glycoprotein that associates with β2 integrin to form the CD11c/CD18 heterodimer that binds CD54 (ICAM-1) and fibrinogen. It is expressed on NK cells, a subset of B and T cells, granulocytes, monocytes, and macrophages. It functions in cytotoxic T cell killing and in neutrophil and monocyte adhesion to endothelium.


Catalog Number: (100243-314)
Supplier: Southern Biotechnology
Description: The CD23 antigen is the low affinity IgE Fc receptor, which is a 45-49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells) and can also be found on the surface of T cells, macrophages and platelets. It is distinct from the high affinity IgE receptors found on basophils and mast cells which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a “membrane bound cytokine," in that the soluble cleavage products of CD23 are themselves able to act as cytokines in vitro.


Catalog Number: (100243-534)
Supplier: Southern Biotechnology
Description: CD45R, also known as B220, a member of the protein tyrosine phosphate family and a major cell surface glycoprotein, represents a restricted form of the CD45 family which primarily recognizes only cells of B-lineage from pro-B cell through mature B lymphocytes and prior to the availability of anti-CD19 monoclonal antibodies was commonly used as a pan B-cell marker. It also reacts with certain activated T cells as well as non-MHC-restricted lytically active lymphokine-activated killer (LAK) cells. In vivo administration of RA3-6B2 has been shown to affect differentiation of both T and B cells in normal mice and reduce the level of anti-DNA antibodies and lymphadenopathies in MRL/lpr mice.


Catalog Number: (100244-266)
Supplier: Southern Biotechnology
Description: Goat Anti-Human IgG-AP antibody for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.


Catalog Number: (100243-134)
Supplier: Southern Biotechnology
Description: CD4 is a type I transmembrane glycoprotein expressed on most thymocytes and the helper/inducer subpopulation of mature T lymphocytes of all mouse strains tested. CD4 has also been detected at low density on pluripotent hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic lymphoid precursors. The CD4 antigen functions as a co-receptor, interacting with class II major histocompatability complex (MHC) molecules in the recognition of foreign antigens by T cells. In vivo and in vitro treatment with the GK1.5 monoclonal antibody effectively depletes CD4+ cells. GK1.5 also blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.


Catalog Number: (100244-966)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Equine IgG(H+L) antibody for use in ELISA, flow cytometry, immunocytochemistry, and western blotting assays.


Catalog Number: (100244-354)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Human Kappa-FITC antibody for use in flow cytometry, immunocytochemistry, and western blotting assays.


Catalog Number: (100245-650)
Supplier: Southern Biotechnology
Description: APC Anti-Human IgM antibody for use in flow cytometry assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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