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Description: The mitochondrial marker antibody is specific for an antigen associated with the mitochondria in human cells. It can be used to stain mitochondria in cell or tissue preparations and as a mitochondrial marker in subcellular fractions.
Catalog Number: 76194-866
Supplier: Prosci


Description: Insulin-regulated facilitative glucose transporter.
Catalog Number: 10069-122
Supplier: Prosci


Description: Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore, BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
Catalog Number: 75788-900
Supplier: Prosci


Description: The M1/70 monoclonal antibody specifically reacts with the 170 kDa alpha M integrin chain of mouse CD11b from the Mac-1 integrin (CD11b/CD18). Mac-1 binds to C3bi, CD54 (ICAM-1), and fibrinogen, and it is expressed by granulocytes, macrophages, NK cells, myeloid-derived dendritic cells, microglia, activated lymphocytes, and mouse B-1 cells. The expression is up-regulated on activated neutrophils at the same time that L-selectin is shed from the cell surface. The M1/70 antibody is used for the detection of monocytes, granulocytes, and a subset of natural killer cells in human peripheral blood.M1/70 blocks C3bi binding and cell adherence, but not cell-mediated lysis and it cross-reacts with human CD11b.
Catalog Number: 10766-158
Supplier: Prosci


Description: TBX18 contains 1 T-box DNA-binding domain. It is a probable transcriptional regulator involved in developmental processes.
Catalog Number: 10101-880
Supplier: Prosci


Description: ZEB2 Antibody: ZEB2, initially identified as Smad interacting-protein 1, is normally located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Like the homologous ZEB1, ZEB2 inhibits the transcription of the E-cadherin gene and induces epithelial-mesenchymal transition, a genetic program controlling cell migration during embryonic development and wound healing, in vitro. ZEB2 can also protect cells from DNA damage-induced apoptosis, suggesting that its expression may contribute to tumor progression. Recent evidence has shown that ZEB2 is often observed in the cytoplasm in numerous cancer tissues, indicating that its localization may be regulated in normal and tumor tissues. Mutations in this gene are also associated with Hirschsprung disease/Mowat-Wilson syndrome.
Catalog Number: 89417-514
Supplier: Prosci


Description: XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. XPO1 also regulates NFAT and AP-1.The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Catalog Number: 10108-006
Supplier: Prosci


Description: DAPK2 Antibody: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as RIP and DAP kinase, are mediators of apoptosis. DAP kinase (DAPK) is pro-apoptotic calcium-regulated serine/threonine kinase containing death domain. Ectopic expression of DAPK induces cell death and suppresses oncogenic transformation. DAPK mediates IFNgamma; induced apoptosis. A novel DAP kinase-related protein was recently identified and designated DAPK2 and DRP-1. Ectopicly expressed DAPK2 induced apoptosis in various types of cells. DAPK has high sequence homology to ZIP kinase and DRAK1/2, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. The messenger RNA of DAPK2 is expressed in multiple human tissues.
Catalog Number: 10749-406
Supplier: Prosci


Description: Polyclonal; Host: Goat; Species Reactiviy: Human; Immunogen: UNC5CL antibody was raised against a 13 amino acid synthetic peptide near the internal region of UNC5CL; Application: ELISA, Western Blot
Catalog Number: 10117-284
Supplier: Prosci


Description: Anti-MAPK1 Rabbit Polyclonal Antibody
Catalog Number: 76763-762
Supplier: Prosci


Description: Anti-HMMR Rabbit Polyclonal Antibody
Catalog Number: 76753-910
Supplier: Prosci


Description: Anti-GPR173 Rabbit Polyclonal Antibody
Catalog Number: 76754-748
Supplier: Prosci


Description: Anti-MCL1 Rabbit Polyclonal Antibody
Catalog Number: 76754-396
Supplier: Prosci


Description: Anti-CHI3L1 Rabbit Polyclonal Antibody
Catalog Number: 76756-364
Supplier: Prosci


Description: Human Recombinant PSCA Protein (from HEK293 cells)
Catalog Number: 77130-162
Supplier: Prosci


Description: NOLC1 Peptide
Catalog Number: 77124-448
Supplier: Prosci


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