Anti-Avelumab Mouse Monoclonal Antibody [clone: 12G9]

Supplier: Genscript
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A02120-40
77007-522EA 153.9 USD
77007-522
Anti-Avelumab Mouse Monoclonal Antibody [clone: 12G9]
Antibodies
Avelumab with trade name Bavencio, is an FDA-approved drug to treat Merkel cell carcinoma, urothelial carcinoma, and renal cell carcinoma. Avelumab is a whole monoclonal antibody of isotype IgG1 that binds to the programmed death-ligand 1 (PD-L1) and therefore inhibits binding to its receptor programmed cell death 1 (PD-1). PD-L1 can be highly expressed on certain tumors, which is thought to lead to reduced activation of immune cells (cytotoxic T-cells in particular) that might otherwise recognize and attack the cancer. Inhibition of PD-L1 by Avelumab can remove this inhibitor effect andMore Product Information
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