Human Recombinant BD1 (from E. coli)

Supplier: PEPROTECH INC.
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300-51A-5UG 300-51A-20UG 300-51A-100UG 300-51A-250UG 300-51A-500UG 300-51A-1MG
10770-762EA 132.81 USD
10770-762 10770-764 10770-766 10770-768 10770-770 10770-772
Human Recombinant BD1 (from E. coli)
Proteins and Peptides

Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Human BD-1 is a 5.0 kDa protein containing 47 amino acid residues.


Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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